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Your questions about genes, nutrition and health, answered

Plain-language answers from 3X4 Genetics on genetic testing, nutrigenomics, metabolism, methylation, healthy ageing and fitness. Start with the quick answer, then read the full guide.

What does a genetic health test actually tell you?

Quick answerA lifestyle genetic test reads variants in the genes that run your metabolism, nutrient processing, detoxification, inflammation and recovery. It does not diagnose disease. It shows how your body tends to work so you can match diet, supplements, exercise and sleep to your biology. The 3X4 Genetics Test uses a simple cheek swab and groups results into 35 pathways across 10 key health areas.

What is nutrigenomics, and can your genes shape your diet?

Quick answerNutrigenomics studies how differences in your genes change the way you respond to food and nutrients. Two people eating the same meal can process fats, carbohydrates, caffeine and vitamins very differently. Genetic testing turns those differences into a Genes First™ starting point for personalised nutrition, used alongside, not instead of, professional guidance.

How do genes affect metabolism and weight?

Quick answerGenes influence appetite signalling, how efficiently you burn or store energy, how you handle blood sugar and how you respond to different macronutrient balances. They do not decide your weight. Knowing your tendencies helps you choose the eating and training approach your body is most likely to respond to, while lifestyle remains the biggest lever.

Methylation, detoxification and oxidative stress: what are these pathways?

Quick answerMethylation, detoxification and antioxidant defence are core biochemical pathways that keep cells running. Variants in genes such as MTHFR, CYP1A2 and GST family genes change how efficiently each pathway works. 3X4 scores the whole pathway rather than a single gene, which is what makes the result actionable for nutrition and lifestyle.

Do your genes decide how you age?

Quick answerGenes set tendencies for inflammation, cellular repair, cognitive resilience and immune function, but how you age is shaped mostly by what you do with that information. Understanding inherited risk and the pathways behind it lets you focus prevention where it matters for you, decades before symptoms would appear.