Genes First™ · Nutrients

The exact nutrients your body actually needs.

B12, folate, choline, vitamin D, omega-3 and more, your genes change how you absorb and use them. Stop guessing.

  • See which nutrients you may need more of
  • End the random-supplement guesswork
  • Tailored nutrition guidance

One test · Results in 2–3 weeks · HSA/FSA eligible

The exact nutrients
Nutrients

The pathways behind what your body absorbs.

Your nutrient requirements are not one-size-fits-all. 3X4 helps you focus on the pathways where genetics has the greatest influence so every recommendation is more strategic and effective.

  1. Vitamin B12

    B12 supports energy production, red blood cell formation, and nervous system health. Your genes can influence how effectively you absorb and utilize it.

  2. Folate

    Folate plays a key role in methylation, DNA repair, and cellular health. Genetic variation can alter folate metabolism and increase your need for targeted support.

  3. Choline

    Choline is essential for brain function, liver health, and cell membrane integrity. Genetics may affect your ability to produce enough choline internally.

  4. Vitamin C

    Vitamin C supports antioxidant defense, collagen production, and immune function. Genetic factors can affect transport and recycling, shaping your ideal intake.

  5. Vitamin D

    Vitamin D influences bone, immune, hormonal, and cardiometabolic health. Your genes can impact both activation and receptor function.

  6. Fatty Acids

    Fatty acids are critical for inflammation balance, cell membranes, and brain health. Genetic insights help you optimize fat quality and omega balance.

Every pathway result explains what it means for you. Your Genes First™ Plan then turns your top three pathways into food recommendations you can act on right away.

Why 3X4

Tailored Nutrition, Built for Your Biology

3X4 translates complex nutrigenetic data into practical actions so you can eat, supplement, and recover in alignment with your unique metabolism.

Targeted Supplement Strategy

Identify where your body may need additional support so you can prioritize high-impact nutrients instead of over-supplementing at random.

Better Absorption Decisions

Learn which nutrients your body may process less efficiently and adjust your nutrition plan to improve uptake and results.

Long-Term Preventive Advantage

Address nutrient-related gaps early to support healthy aging, immune resilience, cardiovascular function, and cognitive performance.

How it works

From a cheek swab to a plan that's actually yours.

01 / 03

Swab at home

No blood, no clinic, no appointment. Register your kit, swab your cheek for 30 seconds, and mail it back, shipping's on us.

5 minutes, start to finish

02 / 03

We read your DNA

Our CAP & CLIA-certified lab analyzes 35 pathways across 10 key health areas, the systems approach practitioners use, not a consumer novelty panel.

Results in 2–3 weeks

03 / 03

Get your plan in the app

Your results live in the 3X4 Health app, plus a downloadable report, with food, lifestyle and supplement guidance built for your genes, not the average person's.

Yours for life, DNA doesn't change

From the community

What people do with their results.

“Knowing my genetics lets me train smarter, not harder. I've already tweaked my diet and lifestyle, and the results? I feel stronger, more energized, and my performance has been next level. And this is just the beginning!”
Brian Mazza@brianmazza
“The 3X4 Genetics test was really helpful for me! It helped me to not have injuries, so it's so important. I think it's one of the main things as a professional player and, of course, every single person.”
Carlos Vela@carlosv11_
“I truly believe in 3X4 and I'm fully integrating the test into my program to make my job easier! The more I learn, the more I'm blown away by everything this test has to offer!”
Kim Lyons@trainerkimlyons
“With this test, I've unlocked the genetic edge to push my ultra-endurance limits—tailoring my nutrition, training, and recovery with pinpoint accuracy has been a total game-changer.”
Matt Johnson@mattjohnson_
“Can't wait to see how 3X4's genetic insights can help me make better personal health choices, and offer another layer of context to guide the individualized coaching we already do at ALTIS.”
Stu McMillan@altis
“I was able to verify some of the things I had already figured out through experimentation that worked for me. And I was able to learn a few more things that I could add to my diet and my supplementation that would actually take my fitness to the next level.”
Kaz
Questions, answered

What people ask about

Can this test tell me which supplements I should prioritize?

Yes. The Nutrients category highlights where your genetics may increase nutrient demand or reduce efficiency, helping you and your practitioner prioritize support more strategically.

What kind of DNA test do you perform?

We utilize a simple, painless cheek swab test that examines key areas of your genome to reveal tailored lifestyle recommendations based on your genetic variants.

Will this help if I already eat healthy?

Absolutely. Even with a healthy diet, genetics can still affect absorption and utilization. Your report helps refine an already strong routine to make it more effective for your biology.

How accurate is at-home genetic testing?

3X4 genetic tests use advanced genomic technologies ensuring high accuracy in identifying genetic markers.

When will I get the test results?

Our lab processes samples in 2-3 weeks on average, and results are delivered digitally to your online account on the same day they are completed.

How will my DNA be protected?

Your genetic privacy is 100% guaranteed. All information and connections are encrypted using SSL, and we follow best practices that align with HIPAA and POPI standards. For more details, read our Privacy Policy.

Is the 3X4 test eligible for HSA/FSA reimbursement?

Yes, it is eligible for HSA / FSA.

How can I use my HSA/FSA debit card?

You would use it in the same way you would use a credit card when paying; simply enter the needed card info. If this does not work, simply pay for the test with your normal credit card, download the invoice/receipt, and submit it for reimbursement.

The cost of guessing

Another year of trial-and-error isn't free.

The 3X4 test is a one-time cost. Guessing is the expensive option.

$1,000s

spent on supplements your body may not even use

Years

of diets and routines built for someone else's biology

Every day

feeling 'off' without knowing why, or what to change

Get my DNA kit

One test · Results in 2–3 weeks · HSA/FSA eligible