Optimal health starts in your cells.
Detoxification, inflammation, methylation and oxidative stress, the cellular processes behind how you feel. See yours.
- Understand your core cellular pathways
- Target inflammation & detox at the source
- A complete, tailored health picture
One test · Results in 2–3 weeks · HSA/FSA eligible

The pathways behind how you feel overall.
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Detoxification
Detoxification is your body’s cleaning crew, clearing out harmful waste to keep your cells healthy.
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Inflammation
Inflammation helps your body heal, but if it lasts too long, it can damage cells and tissues and send your immune system into overdrive.
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Methylation
Methylation works like a dimmer switch, helping your body turn genes, hormones, and brain signals up or down to keep your brain sharp, hormones balanced, and DNA repaired.
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Oxidative Stress
Oxidative stress is like rust in the body, caused by reactive molecules that build up faster than your body can clear them, leading to cell damage and accelerated aging.
Every pathway result explains what it means for you. Your Genes First™ Plan then turns your top three pathways into food recommendations you can act on right away.
The 3X4 Advantage in Genetic Testing for Health
Step into a new era of health optimization with 3X4's advanced genetic testing. Discover:
Tailored Wellness Plans
Tailor your diet & exercise to enhance how your body responds to food and activity for peak physical and mental performance.
Early Detection for Prevention
Learn about hereditary conditions and genetic predispositions, providing valuable information for individualized needs.
Move to Precise Supplement Selection
Identify what exactly your body needs. No more guesswork in selecting the best supplement for your body. Saves you money and prevents over-supplementation.
From a cheek swab to a plan that's actually yours.
Swab at home
No blood, no clinic, no appointment. Register your kit, swab your cheek for 30 seconds, and mail it back, shipping's on us.
5 minutes, start to finish
We read your DNA
Our CAP & CLIA-certified lab analyzes 35 pathways across 10 key health areas, the systems approach practitioners use, not a consumer novelty panel.
Results in 2–3 weeks
Get your plan in the app
Your results live in the 3X4 Health app, plus a downloadable report, with food, lifestyle and supplement guidance built for your genes, not the average person's.
Yours for life, DNA doesn't change
What people do with their results.
“Knowing my genetics lets me train smarter, not harder. I've already tweaked my diet and lifestyle, and the results? I feel stronger, more energized, and my performance has been next level. And this is just the beginning!”
Brian Mazza@brianmazza
“The 3X4 Genetics test was really helpful for me! It helped me to not have injuries, so it's so important. I think it's one of the main things as a professional player and, of course, every single person.”
Carlos Vela@carlosv11_
“I truly believe in 3X4 and I'm fully integrating the test into my program to make my job easier! The more I learn, the more I'm blown away by everything this test has to offer!”
Kim Lyons@trainerkimlyons
“With this test, I've unlocked the genetic edge to push my ultra-endurance limits—tailoring my nutrition, training, and recovery with pinpoint accuracy has been a total game-changer.”
Matt Johnson@mattjohnson_
“Can't wait to see how 3X4's genetic insights can help me make better personal health choices, and offer another layer of context to guide the individualized coaching we already do at ALTIS.”
Stu McMillan@altis
“I was able to verify some of the things I had already figured out through experimentation that worked for me. And I was able to learn a few more things that I could add to my diet and my supplementation that would actually take my fitness to the next level.”
Kaz
What people ask about
Is the heart health genetic test suitable for everyone?
Absolutely. Whether heart and circulation health runs in your family or you just want to take proactive steps, our test provides valuable insights for all.
What kind of DNA test do you perform?
We utilize a simple, painless cheek swab test that examines key areas of your genome to reveal tailored lifestyle recommendations based on your genetic variants.
How is my genetic information used to create a heart health plan?
Your genetic data is analyzed to identify specific genetic predispositions and how your body may respond to various interventions, allowing for a tailored approach to diet, exercise, and lifestyle changes.
How accurate is at-home genetic testing?
3X4 genetic tests use advanced genomic technologies ensuring high accuracy in identifying genetic markers.
When will I get the test results?
Our lab processes samples in 2-3 weeks on average, and results are delivered digitally to your online account on the same day they are completed.
How will my DNA be protected?
Your genetic privacy is 100% guaranteed. All information and connections are encrypted using SSL, and we follow best practices that align with HIPAA and POPI standards. For more details, read ourPrivacy Policy.
Is the 3X4 test eligible for HSA/FSA reimbursement?
Yes, it is eligible for HSA / FSA.
How can I use my HSA/FSA debit card?
You would use it in the same way you would use a credit card when paying; simply enter the needed card info. If this does not work, simply pay for the test with your normal credit card, download the invoice/receipt, and submit it for reimbursement.
Another year of trial-and-error isn't free.
The 3X4 test is a one-time cost. Guessing is the expensive option.
$1,000s
spent on supplements your body may not even use
Years
of diets and routines built for someone else's biology
Every day
feeling 'off' without knowing why, or what to change
One test · Results in 2–3 weeks · HSA/FSA eligible