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Stop Guessing What Your Body Tolerates. Use Genetics to Personalize Sensitivities Support.
Your reactions to caffeine, salt, histamine, iron, and gluten are not random. Discover where your DNA may create higher sensitivity so you can make targeted food and lifestyle changes with confidence.
Guarantee Icon HSA/FSA Eligible
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Fewer Energy Crashes and Jitters Fewer Energy Crashes and Jitters
Smarter Food and Compound Choices Smarter Food and Compound Choices
Calmer Digestion and Daily Comfort Calmer Digestion and Daily Comfort

Decode Your Sensitivity Blueprint

Our genetic analysis helps identify how your body may process common compounds and triggers. With this clarity, you can reduce avoidable discomfort and build a nutrition strategy that aligns with your biology.

Unlock Your Genetic Insights

Take Control of Sensitivities With 3X4 Genetics

Our pathway-based approach translates your genetic profile into practical decisions for food, supplements, and lifestyle. With these insights, you can:

1

Target Your True Triggers

Move beyond trial-and-error elimination diets. Use DNA-backed insights to prioritize the triggers most likely to affect your energy, digestion, and recovery.

2

Personalize Daily Habits

Adjust caffeine timing, sodium intake, and food choices based on how your body may respond, so your plan works with your genetics instead of against it.

3

Improve Comfort and Consistency

Reduce common symptom spikes by building a more precise routine that supports stable energy, better tolerance, and long-term adherence.

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What Do We Test For?

The Sensitivities category helps you understand where your DNA may shape reactions to common dietary compounds and environmental inputs.

SENSITIVITIES CATEGORY:

Caffeine

Caffeine

Genetic differences influence how quickly your body clears caffeine, which can affect sleep quality, focus, stress response, and energy stability.

Salt

Salt

Your genes can impact sodium sensitivity and fluid balance. These insights help guide a more personalized approach to salt intake and cardiovascular support.

Iron Overload

Iron Overload

Some genetic profiles may absorb or store iron differently. Knowing this can help you make safer choices around iron intake and supplementation.

Gluten

Gluten

Genetics can shape how your body responds to gluten-related exposure, informing practical steps to support digestion, comfort, and consistency.

Histamine

Histamine

Variants in histamine-related genes may influence how efficiently histamine is broken down, affecting immune balance, skin, and respiratory comfort.

Address Sensitivities With DNA-Driven Precision

Your results help you prioritize what matters most, so you can move from broad restrictions to targeted, sustainable decisions.

1

Caffeine Metabolism Insight

If you are genetically slower at clearing caffeine, timing and dose matter more. Personalized guidance can improve sleep and daytime performance.

2

Sodium Response Precision

Your genetics can help clarify how sensitive you may be to sodium intake, allowing smarter adjustments to support blood pressure and hydration balance.

3

Iron Management Strategy

When genetic factors suggest higher iron loading risk, targeted monitoring and nutrition decisions can help protect long-term metabolic and liver health.

4

Gluten Tolerance Context

Understanding your genetic context can support better decisions around gluten exposure and symptom tracking for a more effective nutrition plan.

5

Histamine Balance Support

When breakdown pathways are less efficient, precise food and lifestyle adjustments can reduce symptom load and support a calmer immune response.

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Your Journey to DNA-Driven Wellness with 3X4

We aim to give you the tools and understanding to make informed decisions tailored to your genetic profile. Here's how we do it!
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Purchase Your at Home DNA Test Kit
Get your DNA swab kit directly through the app order it through our online store.
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Swab & Send
Follow simple instructions to collect your sample and send it to our lab.
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Access Your Results
Once processed, your results are delivered in-app across 9 health areas.
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Gain Personalized Insights
Start with your highest-impact areas. Get food, lifestyle, and supplement advice based on your genes.

3X4 Success Stories

Learn more about why the 3X4 Test is for you.

Brian Mazza

Brian Mazza

@brianmazza

“Knowing my genetics lets me train smarter, not harder. I've already tweaked my diet and lifestyle, and the results? I feel stronger, more energized, and my performance has been next level. And this is just the beginning!”

Jenny

Jenny

"I took the 3X4 test out of curiosity, not for health issues. The results helped my practitioner treat my skin condition, alleviate perimenopause symptoms, and lose 18 pounds. Now, I use my children's blueprints as references for targeted lifestyle changes. I'm grateful for 3X4, which has inspired me to learn more about my body and its unique environmental interactions."

Carlos Vela

Carlos Vela

@carlosv11_

“The 3X4 Genetics test was really helpful for me! It helped me to not have injuries, so it’s so important. I think it’s one of the main things as a professional player and, of course, every single person. When you are healthy, and you feel good, you can do a lot of things!”

Kim Lyons

Kim Lyons

@trainerkimlyons

“I truly believe in 3X4 and I’m fully integrating the test into my program to make my job easier! The more I learn, the more I’m blown away by everything this test has to offer!”

Matt Johnson

Matt Johnson

@mattjohnson_

“With this test, I’ve unlocked the genetic edge to push my ultra-endurance limits-tailoring my nutrition, training, and recovery with pinpoint accuracy has been a total game-changer.”

Elaine

Elaine

"I had been diagnosed with an aggressive, fast-growing form of breast cancer, but didn't have an explanation what the cause was. Thanks to your tests' guidance, I was able to achieve being in remission (less than 4 months after my 3X4 test results!)"

Stu McMillan

Stu McMillan

@altis

Can't wait to see how 3X4's genetic insights can help me make better personal health choices - and offer another layer of context to guide the individualized coaching we already do at ALTIS.

Kaz

Kaz

"I did the 3X4 Genetics test - I was able to verify some of the things I had already figured out through experimentation that worked for me. And in addition to that I was able to learn a few more things that I could add to my diet and my supplementation that would actually take my fitness to the next level."

Take Control of Sensitivities With Genetics

Replace broad restrictions with precise, DNA-informed choices for daily comfort, better energy, and long-term confidence in your health plan.

Shop 3X4 Genetics Test

Your purchase is eligible for HSA/FSA reimbursement, and your test ships totally free.

Frequently asked questions

No. The 3X4 test is not a diagnostic allergy test. It identifies genetic tendencies that may influence how your body responds to compounds like caffeine, salt, histamine, and gluten, helping guide more personalized decisions.

We utilize a simple, painless cheek swab test that examines key areas of your genome to reveal lifestyle recommendations for weight loss based on your genetic variants.

Yes. Your report helps identify where you may need targeted modifications so you can personalize food choices, timing, and supportive lifestyle habits with greater precision.

3X4 genetic tests use advanced genomic technologies ensuring high accuracy in identifying genetic markers.

Our lab processes samples in 3-4 weeks on average, and results are delivered digitally to your online account on the same day they are completed.

Your genetic privacy is 100% guaranteed. All information and connections are encrypted using SSL, and we follow best practices that align with HIPAA and POPI standards. For more details, read our Privacy Policy.

Yes, it is eligible for HSA / FSA.

You would use it in the same way you would use a credit card when paying; simply enter the needed card info. If this does not work, simply pay for the test with your normal credit card, download the invoice/receipt, and submit it for reimbursement.