Know what to avoid, before it affects you.
Caffeine, salt, gluten, histamine and iron, your genes shape how you respond. Tailor your diet with confidence.
- Find out if you're a fast or slow caffeine metaboliser
- Understand salt, gluten & histamine sensitivity
- Adjust your diet to feel your best
One test · Results in 2–3 weeks · HSA/FSA eligible
The pathways behind what doesn't agree with you.
Your results help you prioritize what matters most, so you can move from broad restrictions to targeted, sustainable decisions.
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Caffeine
Genetic differences influence how quickly your body clears caffeine, which can affect sleep quality, focus, stress response, and energy stability.
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Salt
Your genes can impact sodium sensitivity and fluid balance. These insights help guide a more tailored approach to salt intake and cardiovascular support.
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Iron Overload
Some genetic profiles may absorb or store iron differently. Knowing this can help you make safer choices around iron intake and supplementation.
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Gluten
Genetics can shape how your body responds to gluten-related exposure, informing practical steps to support digestion, comfort, and consistency.
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Histamine Overload
Variants in histamine-related genes may influence how efficiently histamine is broken down, affecting immune balance, skin, and respiratory comfort.
Every pathway result explains what it means for you. Your Genes First™ Plan then turns your top three pathways into food recommendations you can act on right away.
Take Control of Sensitivities With 3X4 Genetics
Our pathway-based approach translates your genetic profile into practical decisions for food, supplements, and lifestyle. With these insights, you can:
Target Your True Triggers
Move beyond trial-and-error elimination diets. Use DNA-backed insights to prioritize the triggers most likely to affect your energy, digestion, and recovery.
Tailor Daily Habits
Adjust caffeine timing, sodium intake, and food choices based on how your body may respond, so your plan works with your genetics instead of against it.
Improve Comfort and Consistency
Reduce common symptom spikes by building a more precise routine that supports stable energy, better tolerance, and long-term adherence.
From a cheek swab to a plan that's actually yours.
Swab at home
No blood, no clinic, no appointment. Register your kit, swab your cheek for 30 seconds, and mail it back, shipping's on us.
5 minutes, start to finish
We read your DNA
Our CAP & CLIA-certified lab analyzes 35 pathways across 10 key health areas, the systems approach practitioners use, not a consumer novelty panel.
Results in 2–3 weeks
Get your plan in the app
Your results live in the 3X4 Health app, plus a downloadable report, with food, lifestyle and supplement guidance built for your genes, not the average person's.
Yours for life, DNA doesn't change
What people do with their results.
“Knowing my genetics lets me train smarter, not harder. I've already tweaked my diet and lifestyle, and the results? I feel stronger, more energized, and my performance has been next level. And this is just the beginning!”
Brian Mazza@brianmazza
“The 3X4 Genetics test was really helpful for me! It helped me to not have injuries, so it's so important. I think it's one of the main things as a professional player and, of course, every single person.”
Carlos Vela@carlosv11_
“I truly believe in 3X4 and I'm fully integrating the test into my program to make my job easier! The more I learn, the more I'm blown away by everything this test has to offer!”
Kim Lyons@trainerkimlyons
“With this test, I've unlocked the genetic edge to push my ultra-endurance limits—tailoring my nutrition, training, and recovery with pinpoint accuracy has been a total game-changer.”
Matt Johnson@mattjohnson_
“Can't wait to see how 3X4's genetic insights can help me make better personal health choices, and offer another layer of context to guide the individualized coaching we already do at ALTIS.”
Stu McMillan@altis
“I was able to verify some of the things I had already figured out through experimentation that worked for me. And I was able to learn a few more things that I could add to my diet and my supplementation that would actually take my fitness to the next level.”
Kaz
What people ask about
Can genetic testing diagnose food allergies or intolerances?
No. The 3X4 test is not a diagnostic allergy test. It identifies genetic tendencies that may influence how your body responds to compounds like caffeine, salt, histamine, and gluten, helping guide more tailored decisions.
What kind of DNA test do you perform?
We utilize a simple, painless cheek swab test that examines key areas of your genome to reveal tailored lifestyle recommendations based on your genetic variants.
Will this help me build a tailored nutrition plan?
Yes. Your report helps identify where you may need targeted modifications so you can tailor food choices, timing, and supportive lifestyle habits with greater precision.
How accurate is at-home genetic testing?
3X4 genetic tests use advanced genomic technologies ensuring high accuracy in identifying genetic markers.
When will I get the test results?
Our lab processes samples in 2-3 weeks on average, and results are delivered digitally to your online account on the same day they are completed.
How will my DNA be protected?
Your genetic privacy is 100% guaranteed. All information and connections are encrypted using SSL, and we follow best practices that align with HIPAA and POPI standards. For more details, read our Privacy Policy.
Is the 3X4 test eligible for HSA/FSA reimbursement?
Yes, it is eligible for HSA / FSA.
How can I use my HSA/FSA debit card?
You would use it in the same way you would use a credit card when paying; simply enter the needed card info. If this does not work, simply pay for the test with your normal credit card, download the invoice/receipt, and submit it for reimbursement.
Another year of trial-and-error isn't free.
The 3X4 test is a one-time cost. Guessing is the expensive option.
$1,000s
spent on supplements your body may not even use
Years
of diets and routines built for someone else's biology
Every day
feeling 'off' without knowing why, or what to change
One test · Results in 2–3 weeks · HSA/FSA eligible