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Life is short.It doesn’t have to be.

Most DNA tests hand you raw data and leave you to make sense of it. 3X4 reads how your genes work together and turns it into actionable guidance across 10 health areas, so you can live a longer, healthier life.

Get Your Test Kit Download a Sample Report
9,000+ practitioners CAP & CLIA-certified lab HSA / FSA eligible Patented pathway approach

Trusted by9,000+ practitioners.

Practitioners, organizations, and professional sports teams

Next Health Canyon Ranch Parsley Health Forum Health Cenegenics NutriDyn UltraWellness Center LivingPlate Rx Fullscript HealthLynked Eleven Eleven Premier Integrative Health Lumati Quotient Health Functional Medical Institute Metabolic Terrain Institute Orange County SC AC Cesena

What you learn

10 health areas.35 pathways.

Discover your foundation behind every diet, supplement, and workout.

PowerRecoveryEnduranceInjuryTraining Response
Glucose & Insulin
Mood & BehaviorMemory
DetoxificationInflammationMethylationOxidative Stress
Blood PressureBlood ClottingVascular HealthCholesterol
Hormone Balance
Muscle HealthCollagen & JointsBone Health
Vitamin B12FolateCholineVitamin CVitamin DFatty Acids
CaffeineSaltIron OverloadGlutenHistamine Overload
AppetitePro-Inflammatory FatFat StorageEnergy Expenditure

How it works

Genetics,made easy.

1
60 seconds

Order your kit

Ships free to your door. A painless cheek swab, done in 60 seconds.

2
5 minutes

Ship it back

No blood draw, no clinic. Drop the sealed sample at any FedEx location with the prepaid label.

3
2–3 weeks

Lab analysis

Our CAP & CLIA-certified partner lab reads your DNA. Our proprietary DARWIN algorithm integrates the markers into 35 pathway results.

4
Lifetime access

Your Genes First™ Plan

Tailored food and lifestyle guidance, plus a downloadable PDF report, yours for life in the 3X4 Health app.

Get your test kit

Reviews

Real people.Real stories.

  • Testimonial, Jenna
    Jenna

    “Turns out my DNA had the answers I was missing.”

  • Testimonial, Leslie
    Leslie

    “I wasn’t dealing with multiple health issues — I was dealing with one story I didn’t know how to read yet.”

  • Testimonial, Grace
    Grace

    “How cool would it be if our bodies came with an instruction manual?”

  • Testimonial, Candice
    Candice

    “You don’t look at the symptoms — you look upstream.”

  • Testimonial, Brian Mazza
    Brian Mazza

    “It’s not about guessing anymore — it’s about knowing.”

  • Testimonial, Dr Perlmutter
    Dr Perlmutter

    “When we understand our uniqueness, we’re really a leg up for longevity.”

  • Testimonial, Dr Becky
    Dr Becky

    “Your body runs on entire biological pathways, not isolated genes.”

“Knowing my genetics lets me train smarter, not harder. I added 35 lbs to my deadlift PR in 8 weeks. I feel stronger, more energized, and my performance has been next level.”

Brian MazzaBrian MazzaEntrepreneur & performance athlete

“After doing this test, I realized how much better I could’ve taken care of myself if I had this information earlier. Knowing exactly how your body works, what it needs, what to avoid, it changes everything. I honestly wish I had this at the start of my career.”

Carlos VelaCarlos VelaProfessional footballer

“I truly believe in 3X4. The more I learn, the more I’m blown away. My sleep score jumped from 71 to 92, and I’m integrating it into every program.”

Kim LyonsKim LyonsTrainer & coach

“I’ve unlocked the genetic edge for my ultra-endurance limits. Recovery between long runs is down 40%.”

Matt JohnsonMatt JohnsonUltra-endurance athlete

“If we know our genes, we know not how we’re going to die, we know how we’re going to live.”

Dr. Jeffrey BlandDr. Jeffrey BlandPhD, FACN, FACB, CNS

“These insights sharpened my own health choices and added real context to how we coach.”

Stu McMillanStu McMillanPerformance coach, ALTIS

The science

The gold standardfor genetic testing.

Built on 25+ years of peer-reviewed nutrigenomics and processed through a CAP & CLIA-certified lab. Consistent, reliable results your practitioner can act on.

Explore the sample report
Dr. Frank Lipman

“Using 3X4 Genetics is essential for all my patients because you can really target their treatment. Using genetics enables me to take my patients to a whole other level of health.”

Dr. Frank Lipman, MD
Functional medicine pioneer
9,000+
Practitioners
50
US states
4
Countries
25+
Years peer-reviewed

Your plan

See your reportbefore you buy.

Every pathway comes back with a clear, plain-language readout and a specific action, not a wall of raw data. This is the same format as your real results.

Open the sample report
Genes First™ PlanSample · Pathway results
Fat StorageVery High

Your genes favor fat storage, so weight can climb even on moderate intake.

InflammationHigh

Your cells manage inflammation less easily, which can wear on long-term health.

Blood PressureMedium

Well regulated for now, but stress, poor sleep, or strain can tip the balance.

EnduranceLow

You respond more slowly to endurance training, so consistency is what moves the needle.

The only health testyou’ll buy once.

No subscriptions, no renewals. One test, read for life, because your genes never change.

“Is it worth it?”Most people spend more than this every year on supplements they are guessing at. This tells you which ones your body can actually use.
“Do I pay every month?”No. It is a one time test with lifetime access to your report and updates as the science grows.
“Can I use my benefits?”Yes. It is HSA and FSA eligible, so you can put pre-tax dollars toward it.

3X4 Genetics Test

$299

one time, yours for life

about 82 cents a day in your first year

  • 10 health areas and 35 pathways analyzed
  • Free shipping and prepaid return
  • Lifetime access in the 3X4 Health app
  • No subscription, ever
  • HSA and FSA eligible
1
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Secure checkout. Free shipping in the US.

Frequently asked questions

3X4 Genetics is an at-home DNA test that turns your genetics into a tailored health and nutrition plan. Built on pathway-based nutrigenomics, 3X4 reads how your genes work together across 10 health areas and 35 pathways, then delivers a Genes First™ Plan: clear, actionable guidance on what to eat, which supplements to take, and how to train, move, and age well.
23andMe is primarily an ancestry test that reports where your DNA comes from, while 3X4 Genetics is a health and wellness DNA test built for action. Instead of a raw data dump, 3X4 analyzes only genes with strong scientific validity and reads them together as pathways, producing specific diet, supplement, and lifestyle recommendations. In short: an ancestry test like 23andMe tells you about your heritage; 3X4 tells you what to do about your health.
No, you do not need to see a 3X4 Practitioner to receive your report. But when your genetic insights are combined with your medical history, unique lifestyle, diet preferences, and exercise choices, a fuller picture starts to emerge. If you are looking for a detailed, tailored action plan, our practitioner partners are ready to guide your next steps.
Taking the 3X4 Genetics Test is a simple at-home cheek swab that takes about 60 seconds, with no blood draw and no clinic visit. Your kit ships free, and you ship the sealed sample back using the prepaid return label included in the box.
Your 3X4 results are ready in the 3X4 Health app about 2 to 3 weeks after your sample reaches the lab. Your DNA is processed by a CAP & CLIA-certified laboratory, then our proprietary DARWIN algorithm integrates your markers into your Genes First™ Plan across all 35 pathways.
Your DNA does not change, so you only take the 3X4 test once. What does grow is the science: as nutrigenomics research advances, your report and recommendations are updated in the app at no extra cost. One test becomes a resource you can reference for the rest of your life.
Data privacy is a top priority for us. We treat your personal information with the rigor and integrity it deserves, and our practices, procedures, policies, and technology are designed to safeguard your privacy and health data. All information and connections are encrypted using SSL, and we follow best practices that align with HIPAA and POPI standards. For more details, check out How 3X4 Protects Genetic Data and read through our Privacy Policy.
See all frequently asked questions

One test.A lifetime of answers.

Get your test kit

Genes First™: health that starts in your DNA.