Genes First™ · Heart

Protect your heart with a plan built on your genes.

Blood pressure, cholesterol, clotting and vascular health are all shaped by your DNA. Get ahead of them.

  • Know your blood pressure & cholesterol genes
  • Understand your vascular and clotting risk
  • Prevention guidance tailored to you

One test · Results in 2–3 weeks · HSA/FSA eligible

Protect your heart with a plan
Heart & vascular

The pathways behind heart health.

Heart health has four dedicated pathways in your report. Each one is read from your DNA and explained in plain English, with what it means for you.

  1. Blood Pressure

    High blood pressure is associated with damage to the artery wall and fluid retention in the blood vessel which can affect your circulation and heart health.

  2. Blood Clotting

    Blood clotting is a survival tactic to prevent uncontrolled bleeding but may cause harm when the formation and breakdown of clots is inefficient.

  3. Vascular Health

    The integrity of arteries and veins affects blood flow and the development of chronic conditions.

  4. Cholesterol

    Cholesterol metabolism is influenced by how various fats are processed and stored within the blood vessels and is essential for building cell membranes, producing hormones, and making vitamin D.

Every pathway result explains what it means for you. Your Genes First™ Plan then turns your top three pathways into food recommendations you can act on right away.

Why 3X4

Get Your Heart in Harmony.

With a focus on precision and empathy, our genetic testing offers a new perspective on heart health care, enabling you to:

Predict and Prevent

Understand if your genes expose you to any heart issues and plan how to lower those predispositions.

Eat with Genetic Intelligence

Make smart nutrition choices by selecting foods that match your genetic needs for a healthier heart.

DNA-Driven Fitness

Discover heart-strengthening exercises that are perfect for your genetic makeup.

How it works

From a cheek swab to a plan that's actually yours.

01 / 03

Swab at home

No blood, no clinic, no appointment. Register your kit, swab your cheek for 30 seconds, and mail it back, shipping's on us.

5 minutes, start to finish

02 / 03

We read your DNA

Our CAP & CLIA-certified lab analyzes 35 pathways across 10 key health areas, the systems approach practitioners use, not a consumer novelty panel.

Results in 2–3 weeks

03 / 03

Get your plan in the app

Your results live in the 3X4 Health app, plus a downloadable report, with food, lifestyle and supplement guidance built for your genes, not the average person's.

Yours for life, DNA doesn't change

From the community

What people do with their results.

“Knowing my genetics lets me train smarter, not harder. I've already tweaked my diet and lifestyle, and the results? I feel stronger, more energized, and my performance has been next level. And this is just the beginning!”
Brian Mazza@brianmazza
“The 3X4 Genetics test was really helpful for me! It helped me to not have injuries, so it's so important. I think it's one of the main things as a professional player and, of course, every single person.”
Carlos Vela@carlosv11_
“I truly believe in 3X4 and I'm fully integrating the test into my program to make my job easier! The more I learn, the more I'm blown away by everything this test has to offer!”
Kim Lyons@trainerkimlyons
“With this test, I've unlocked the genetic edge to push my ultra-endurance limits—tailoring my nutrition, training, and recovery with pinpoint accuracy has been a total game-changer.”
Matt Johnson@mattjohnson_
“Can't wait to see how 3X4's genetic insights can help me make better personal health choices, and offer another layer of context to guide the individualized coaching we already do at ALTIS.”
Stu McMillan@altis
“I was able to verify some of the things I had already figured out through experimentation that worked for me. And I was able to learn a few more things that I could add to my diet and my supplementation that would actually take my fitness to the next level.”
Kaz
Questions, answered

What people ask about

Is the heart health genetic test suitable for everyone?

Absolutely. Whether heart and circulation health runs in your family or you just want to take proactive steps, our test provides valuable insights for all.

What kind of DNA test do you perform?

We utilize a simple, painless cheek swab test that examines key areas of your genome to reveal tailored lifestyle recommendations based on your genetic variants.

How is my genetic information used to create a heart health plan?

Your genetic data is analyzed to identify specific genetic predispositions and how your body may respond to various interventions, allowing for a tailored approach to diet, exercise, and lifestyle changes.

How accurate is at-home genetic testing?

3X4 genetic tests use advanced genomic technologies ensuring high accuracy in identifying genetic markers.

When will I get the test results?

Our lab processes samples in 2-3 weeks on average, and results are delivered digitally to your online account on the same day they are completed.

How will my DNA be protected?

Your genetic privacy is 100% guaranteed. All information and connections are encrypted using SSL, and we follow best practices that align with HIPAA and POPI standards. For more details, read ourPrivacy Policy.

Is the 3X4 test eligible for HSA/FSA reimbursement?

Yes, it is eligible for HSA / FSA.

How can I use my HSA/FSA debit card?

You would use it in the same way you would use a credit card when paying; simply enter the needed card info. If this does not work, simply pay for the test with your normal credit card, download the invoice/receipt, and submit it for reimbursement.

The cost of guessing

Another year of trial-and-error isn't free.

The 3X4 test is a one-time cost. Guessing is the expensive option.

$1,000s

spent on supplements your body may not even use

Years

of diets and routines built for someone else's biology

Every day

feeling 'off' without knowing why, or what to change

Get my DNA kit

One test · Results in 2–3 weeks · HSA/FSA eligible