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Personalized performance insights
Nutrition strategies tailored to your DNA
Know exactly which supplements you need
Founder, HPLT
Knowing my genetics lets me train smarter, not harder. I've already tweaked my diet and lifestyle, and the results? I feel stronger, more energized, and my performance has been next level. This is just the beginning.
Brian Mazza
Founder, HPLT · @brianmazza
Why HPLT Athletes Choose 3X4 Genetics
HPLT teaches you to train for life. 3X4 shows you the genetic blueprint underneath it—so the work you put in actually fits your biology.
Train Smarter
See how your genes influence muscle, joint, and tendon performance—so you can build strength and stay durable for the long game.
Fuel With Precision
Your body metabolizes carbs, fats, and caffeine differently. Get nutrition strategies built for your DNA, not the latest diet trend.
Recover Faster
Discover your inflammation, oxidative stress, and detox profile—so you can dial in sleep, supplementation, and recovery protocols that actually work.
Built For Longevity
Cardiovascular, hormonal, and metabolic insights that help you perform today and stay healthy for decades to come.
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Your Genetic Blueprint for Performance & Longevity.
Personalized. Science-Backed. Actionable.
Through a simple cheek swab, the 3X4 Genetics Test analyzes 36 genetic pathways across 9 key health areas—including muscle health, cardiovascular performance, inflammation, hormones, and nutrient metabolism.
Using 25 years of relevant research and our advanced AI technology, we deliver personalized recommendations so you can train smarter, recover faster, and fuel your body based on what your DNA actually needs—for a lifetime of high performance.
Simple Steps to Your Genetic Edge
Athletes Who Train Smarter With 3X4
See why top athletes and high performers trust 3X4 Genetics to optimize their performance.
Matt Johnson
@mattjohnson_
“With this test, I've unlocked the genetic edge to push my ultra-endurance limits—tailoring my nutrition, training, and recovery with pinpoint accuracy has been a total game-changer.”
Carlos Vela
@carlosv11_
“After doing this test, I realized how much better I could've taken care of myself if I had this information earlier. Knowing exactly how your body works—what it needs, what to avoid—it changes everything. I honestly wish I had this at the start of my career.”
Stu McMillan
@altis
Can't wait to see how 3X4's genetic insights can help me make better personal health choices — and offer another layer of context to guide the individualized coaching we already do at ALTIS.
Kim Lyons
@trainerkimlyons
“I truly believe in 3X4 and I'm fully integrating the test into my program to make my job easier! The more I learn, the more I'm blown away by everything this test has to offer!”
Kaz
"I did the 3X4 Genetics test - I was able to verify some of the things I had already figured out through experimentation that worked for me. And in addition to that I was able to learn a few more things that I could add to my diet and my supplementation that would actually take my fitness to the next level."
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Ready to Train For Life — Built On Your DNA?
Join thousands of athletes who have optimized their training, nutrition, and recovery with 3X4 Genetics. As part of the HPLT community, you get exclusive offers on both the single test and the bundle.
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