Your pathways, ranked
The plan starts from your highest-impact genetic pathways, so your effort goes where your biology says it matters most.
Your DNA, turned into a clear plan.
Most genetic tests hand you raw data and leave you to sort it out. The Genes First™ Plan is a tailored plan for food, supplements, and lifestyle, built from the way your genetic pathways work together. It lives in the 3X4 Health app and comes with every 3X4 Genetics Test.
Trusted by 9,000+ practitioners across every specialty. Included with every test — no subscription, no upsell.
See it in action.
A quick walkthrough of the Genes First™ Plan in the 3X4 Health app.
New in the 3X4 Health app
Inside your Genes First™ Plan.
Most plans start with averages. Yours starts with your DNA. Open the app and see exactly what your genes are asking for, and what to do about it, one day at a time.
Daily food, supplement, and lifestyle actions
Clear, specific actions for every day — what to eat, what to take, and how to live, translated from your results.
The "why" behind every recommendation
Every action links back to the genes and pathways that drive it, explained in plain language you can actually use.
Already tested with 3X4?
Your Genes First™ Plan is ready.
No new test. No new sample. No payment. Your plan is generated from the 3X4 Genetics Test you already did with us — open the app, answer a quick intake, and it's yours.
The Genes First™ approach
Health advice that starts with you.
Genes don't work alone. Why would your testing? Genes First™ means your DNA is the starting point for every recommendation we make.
Pathways, not single genes
We look at how your biology works together, not isolated genes. Most tests report gene by gene; your plan is built from whole pathways.
Built from your DNA
Every recommendation starts with your genetic blueprint — not diet trends, not population averages, not a quiz.
Actions you can follow
Your plan translates the science into clear food, supplement, and lifestyle actions for every day. No data dump, no guesswork.
35
Pathways behind your plan
10
Key health areas
9,000+
Trusted by 9,000+ practitioners
From test to plan, in three steps.
1
Take the test
Order the 3X4 Genetics Test and complete your at-home cheek swab — no blood, no lab visit. Already tested? Skip straight to step three.
2
Get your results
Your genetic pathway results arrive in the 3X4 Health app — 35 pathways across 10 health areas, explained in plain language.
3
Answer a quick intake, get your plan
Tell us about your preferences — like the foods you avoid — so the plan fits your real life. Then follow clear actions built from your DNA.
Don't have a 3X4 Genetics Test yet?
One test, all-inclusive: 35 pathways, gene-level detail, and your Genes First™ Plan.
Questions, answered.
What exactly is the Genes First™ Plan?
A tailored plan built from your 3X4 Genetics Test results. It translates your genetic pathways into clear food, supplement, and lifestyle actions inside the 3X4 Health app.
Does it cost extra?
No. The Genes First™ Plan is included with every 3X4 Genetics Test at no additional cost — and if you've already tested with 3X4, it's generated from the results you already have.
I've already taken the test. How do I get my plan?
Update to the newest version of the 3X4 Health app, open it, and answer a quick intake about your preferences. Your plan is generated from your existing results — no new test, no new sample.
Does the plan change over time?
Your plan is built once from your DNA and your intake, and it's designed for you to follow at your own pace. Your genes don't change — so your plan stays your reliable foundation.
How do I take the test?
With an at-home cheek swab — no blood draw, no lab visit. Ship it back in the prepaid package and your results arrive in the 3X4 Health app.
Is my data safe?
Your plan lives inside the same 3X4 Health account as the rest of your results, with the same access controls. For full detail on how your data is handled, see our privacy policy.
Start with your genes.
Take the 3X4 Genetics Test and get your Genes First™ Plan the moment your results are ready — or open the app if you've already tested.