Why your energy dips in the same ways every day
Variants in your detoxification and mitochondrial-function genes shape how your body manages energy across the day. It's not a willpower issue.
How your genes are expressed shapes the decisions your body makes every single day. Here's why that changes everything about how you approach your health.
One test · Results in 2–3 weeks · HSA/FSA eligible

For decades, health advice has been built for the average person, but your biology is not average. Here's what changes when you start with your genes.
Variants in your detoxification and mitochondrial-function genes shape how your body manages energy across the day. It's not a willpower issue.
Your genetic variants for appetite, fat storage, and fatty acid metabolism decide what a good-for-you plate actually looks like.
If your body doesn't convert or absorb nutrients well, supplementing it blindly rarely delivers what you're hoping for.
Most genetic health tests report on individual variants in isolation, a single gene, a single marker. They tell you what you have. They don't tell you how it moves in the context of how your entire biochemistry connects.
3X4 maps your genetics across 35 biochemical pathways, the actual functional chains that run your biology: detoxification, methylation, hormone balance, fat storage, inflammation. We show how they connect across 10 health areas.
Your genetic report maps to all ten, not in isolation, but in relation to each other, the way your body actually works.
Cellular
4 pathways. Detoxification, inflammation, methylation, oxidative stress.
Brain
2 pathways. Mood & behaviour, memory.
Heart & Vascular
4 pathways. Blood pressure, blood clotting, vascular health, cholesterol.
Weight
4 pathways. Appetite, pro-inflammatory fat, fat storage, energy expenditure.
Hormones
1 pathway. Hormone balance.
Blood Sugar Regulation
1 pathway. Glucose & insulin.
Muscle & Skeletal
3 pathways. Muscle health, collagen & joints, bone health.
Sensitivities
5 pathways. Caffeine, salt, iron overload, gluten, histamine.
Nutrients
6 pathways. Vitamin B12, folate, choline, vitamin C, vitamin D, fatty acids.
Activity
5 pathways. Injury, endurance, power, recovery, training response.
35 pathways across 10 health areas, every one of them read from a single cheek swab.
Real questions from real people and what genetics reveals about them.
Genetic variants across PPARG and FTO influence how your body stores fat and regulates appetite. The plate that works for you reflects those genes, not generic macro rules.
A good chunk of typical supplement stacks end up treating needs your body never had. 3X4 shows exactly which nutrients you convert efficiently and which you don't.
Genetic variants in your COMT and CYP genes shape your nervous-system tone and stress response. Understanding them lets you match your routine to the biochemistry you actually have.
Inflammation genetics, oxidative stress, and recovery capacity are genetic. Understanding them lets you train with your biology, not against it.
3X4 Health does not sell, share, or monetize your genetic data. It stays encrypted and under your control, full stop.
3X4 doesn't diagnose, predict, or screen for anything clinical. It maps how your biology works so you can optimize the things you control such as food, sleep, supplements, movement.
The genes we report on are supported by decades of peer-reviewed research. No astrology-grade wellness claims just the biochemistry that actually drives how your body works.
Your genes don't act in isolation. We map how they interact across the biochemical chains that actually run your biology.
From cellular health to cardiovascular, weight to hormones, 3X4 connects every result back to the system that drives it.
Your genes don't change. Take the test once, the actionable recommendations work for life.
See the full 3X4 sample report: all 35 pathways across the 10 health areas, laid out exactly as you'd receive them.
Free. No credit card. Private and encrypted.
Our test analyzes gene results known to influence metabolism, fat storage, and nutrition absorption to provide highly accurate insights into how your body responds to diet and exercise.
We utilize a simple, painless cheek sample collection test that examines key areas of your genome to reveal tailored lifestyle recommendations based on your genetic variants.
Absolutely, DNA-guided meal plans and exercise routines are aligned with your genetic predispositions, helping your results feel more sustainable than conventional, one-size-fits-all approaches.
No, the test provides tailored insights and actionable steps so your nutritionist and trainer can fine-tune existing plans to better fit your genetic makeup.
Our processing centre samples in 2-3 weeks on average and results are delivered digitally to your online account that same day they are completed.
Your genetic privacy is 100% guaranteed. All information and connections are encrypted using SSL and we follow best practices that align with HIPAA and POPI standards. For more details read through our Privacy Policy.
Yes, it is eligible for HSA / FSA.
You would use it in the same way you would use a credit card when paying, simply enter the needed card info. If this does not work, simply pay for the test with your normal credit card, download the invoice/receipt and submit that for reimbursement.
One cheek swab. Results in 2–3 weeks. 35 pathway results across 10 health areas, with food, lifestyle and supplement guidance tailored to how your body actually works.
One test · Results in 2–3 weeks · HSA/FSA eligible