Skip to content
Genes-First Health

Your genes don't predict your fate. They explain it.

How your genes are expressed shapes the decisions your body makes every single day. Here's why that changes everything about how you approach your health.

Why, not just what.

Most people are trying to fix symptoms. Genetics reveals the source.

For decades, health advice has been built for the average person, but your biology is not average. Here's what changes when you start with your genes.

01

Why your energy dips in the same ways every day

Variants in your detoxification and mitochondrial-function genes shape how your body manages energy across the day. It's not a willpower issue.

02

Why the diet that worked for someone else doesn't work for you.

Your genetic variants for appetite, fat storage, and fatty acid metabolism decide what a good-for-you plate actually looks like.

03

Why you keep taking supplements and feeling no different.

If your body doesn't convert or absorb nutrients well, supplementing it blindly rarely delivers what you're hoping for.

The 3X4 approach

Not a list of risks. A map of how you work.

Most genetic health tests report on individual variants in isolation, a single gene, a single marker. They tell you what you have. They don't tell you how it moves in the context of how your entire biochemistry connects.

3X4 Health
Detoxification Inflammation Methylation OxidativeStress Mood &Behaviour Memory BloodPressure BloodClotting VascularHealth Cholesterol Appetite Pro-Inflam.Fat FatStorage EnergyExpenditure HormoneBalance Glucose &Insulin MuscleHealth Collagen &Joints BoneHealth Caffeine Salt IronOverload Gluten Histamine VitaminB12 Folate Choline VitaminC VitaminD FattyAcids 30 PATHWAYS

3X4 maps your genetics across 30 biochemical pathways, the actual functional chains that run your biology: detoxification, methylation, hormone balance, fat storage, inflammation. We show how they connect across 9 health systems.

Tap a pathway to see what connects

Maps genes across 30 interconnected pathways

Focused entirely on lifestyle optimization

Actionable across 9 health areas

Your specific blueprint, not population averages

9 health systems

Every test result you will ever get connects back to these systems.

Your genetic report maps to all nine, not in isolation, but in relation to each other, the way your body actually works.

Cellular

4 pathways

Detoxification, inflammation, methylation, oxidative stress

Brain

2 pathways

Mood & behaviour, memory

Heart & Vascular

4 pathways

Blood pressure, blood clotting, vascular health, cholesterol

Weight

4 pathways

Appetite, pro-inflammatory fat, fat storage, energy expenditure

Hormones

1 pathway

Hormone balance

Blood Sugar Regulation

1 pathway

Glucose & insulin

Muscle & Skeletal

3 pathways

Muscle health, collagen & joints, bone health

Sensitivities

5 pathways

Caffeine, salt, iron overload, gluten, histamine

Nutrients

6 pathways

Vitamin B12, folate, choline, vitamin C, vitamin D, fatty acids

Why, not just what

The guesswork in your health decisions has a better alternative.

Real questions from real people and what genetics reveals about them.

01

I eat well and exercise. Why is weight management still a constant struggle?

Genetic variants across PPARG and FTO influence how your body stores fat and regulates appetite. The plate that works for you reflects those genes, not generic macro rules.

02

Am I really getting the most from the supplements I take?

A good chunk of typical supplement stacks end up treating needs your body never had. 3X4 shows exactly which nutrients you convert efficiently and which you don't.

03

I'm always exhausted despite sleeping 8 hours a night.

Genetic variants in your COMT and CYP genes shape your nervous-system tone and stress response. Understanding them lets you match your routine to the biochemistry you actually have.

04

Why do I feel like I'm always one hard workout away from burnout?

Inflammation genetics, oxidative stress, and recovery capacity are genetic. Understanding them lets you train with your biology, not against it.

Your genetic data belongs to you. Only you.

3X4 Health does not sell, share, or monetize your genetic data. It stays encrypted and under your control, full stop.

Not a diagnostic test.

3X4 doesn't diagnose, predict, or screen for anything clinical. It maps how your biology works so you can optimize the things you control such as food, sleep, supplements, movement.

Built on systems biology, not pop-science.

The genes we report on are supported by decades of peer-reviewed research. No astrology-grade wellness claims just the biochemistry that actually drives how your body works.

The numbers behind it

Depth is the difference between data and understanding.

30

Biochemical pathways mapped

Your genes don't act in isolation. We map how they interact across the biochemical chains that actually run your biology.

9

Health systems covered

From cellular health to cardiovascular, weight to hormones, 3X4 connects every result back to the system that drives it.

1x

One test. One lifetime.

Your genes don't change. Take the test once, the actionable recommendations work for life.

Your 2-minute gene check

Could it be your genes?

Answer a handful of questions about how you feel, eat, and move. We'll point to the pathways your DNA most likely influences and what you can do about it.

Your answers stay with you. We never share or sell your data.