Skip to content

Rethink Weight Loss With Genetic Testing

You are unique. Your plan should be too. Break from the one-size-fits-all and tailor your diet and exercise plan to your unique genetic makeup for faster, more sustainable results.

No More Trial & Error - Your DNA Reveals Your Optimal Lifestyle Plan

Our genetic tests analyze 157 genes related to nutrition, energy metabolism, fat storage, fitness and more. We examine how your DNA uniquely responds to different foods and nutrients. With genetic insights, you can make a health plan that works with your biology, not against it.

Take Control With DNA Insights

Change the Game with 3X4

Our DNA testing maps out your genetic blueprint, providing a foundation of insights about your body. With this blueprint, your nutritionists can customize an optimal weight loss plan, that will empower you to:

1

Move with Intention

Discover the types of exercise that work best for your body and make fitness enjoyable.

2

Outsmart the Plateau

Support your hormone pathways with targeted strategies based on your DNA, and watch the pounds start melting.

3

Prevent Weight Regain

Understand your risk factors for weight regain and develop a personalized plan to stay on track.

What Do We Test For?

3X4 decodes your DNA to offer tailored insights into how the unique Energy & Activity Pathways reveal predispositions for performance, adipogenesis (fat storage), energy expenditure, exercise response, appetite and satiety, weight management, and more, empowering you to build a customized workout plan.

ACTIVITY PATHWAYS:

Performance

Performance

Understand your natural athletic potential and how your body responds to different training types.

Performance

Injury Risk

Identify areas where you're more susceptible to injuries and get proactive with preventive measures.

Performance

Training Response

Your genetics plays a significant role in influencing your baseline fitness level, as well as your response to aerobic training.

Performance

Recovery Secrets

Discover the genetic factors impacting post-workout recovery to optimize your recovery plan for faster results.

ENERGY PATHWAYS:

Fat Metabolism

Fat Metabolism

Learn how your body processes and stores fat, and how you can optimize your diet for better energy management.

Fat Metabolism

Calorie Burn

See how your genetics impacts resting and active calorie expenditure. Get tailored tips to boost metabolism.

Fat Metabolism

Exercise Response

Genes shape how your body uses stored fat for exercise fuel. Understand the most effective way to exercise for your unique physiology.

Fat Metabolism

Appetite Control

Regulate your appetite with insights into your genetic tendencies influencing hunger/satiety signals and overeating risk.

What’s Included in Your Test Reports?

Our report covers 36 metabolic pathways across 6 health categories.

Cellular Fitness

Optimize vital cellular processes. Get coverage of key metabolic processes like methylation, oxidative stress, detoxification, and inflammation regulation.

System Imbalances

Identify potential risks related to crucial systems so you can take proactive steps to support healthy blood sugar balance, brain function, bone health, mood regulation, and hormone equilibrium.

Cardiovascular Health

Understand your unique risk factors for vascular issues, high cholesterol, hypertension, and circulation problems so you can prioritize lifestyle changes and preventive action before the disease develops.

Energy Systems

Identify reasons you may struggle with weight management, or exercise intolerance so you can correct metabolism and appetite imbalances and rediscover resilient energy levels.

Activity Potential

Uncover your body's strengths and limitations for power, endurance, injury recovery, and training response. This allows customized fitness programming so you can actualize athletic potential while preventing injury.

Nutrient Needs

Determine which vitamins, minerals, and nutrients you uniquely require more or less of due to genetic factors. Then supplement and adjust your diet appropriately to maximize the benefits.

Your Journey to DNA-Driven Wellness with 3X4

We aim to give you the tools and understanding to make informed decisions tailored to your genetic profile. Here’s how we do it!

Purchase Your Home DNA Test Kit

01. Purchase Your Home DNA Test Kit

Order our simple cheek swab kit, which will be mailed to your door. Clear instructions walk you through quick, easy sample collection.

Send Us Your DNA Sample

02. Send Us Your DNA
Sample

Ship back the cheek swab kit in our prepaid mailer. Our lab partners use advanced genomic technology to extract and analyze your genetic data reliably.

Let us Analyze Your Genes

03. Let us Analyze Your Genes

Our experts examine 157 key genes related to lifestyle areas such as nutrition, weight loss, and fitness. We examine complex interactions and pathways to uncover insights.

Receive Your Personal DNA Blueprint

04. Receive Your Personal DNA Blueprint

In a customized report, you’ll receive a detailed blueprint showing how your body uniquely functions plus science-backed recommendations on diet, fitness, lifestyle and more - so you can optimize well-being.

Trusted By Industry Leaders

3X4 Success Stories

Still unsure if 3X4 is right for you? Explore firsthand testimonials from our customers. Here’s what they had to say:

Profile Picture

Janel, 30

Verified

@janel003

“I found out what my body was lacking and with the right dietitian, I now know what diet, exercise, and supplements my body needs.
➡ I lost 14 kgs
➡ I have way more energy
➡ My skin is radiant
➡ I sleep very well
➡ I am more focused and less overwhelmed
➡ Even my house is more organized.”

Profile Picture

Aaron, 50

Verified

@aaron

“I learned how my body reacts to strength and speed training vs. longer/slower endurance training. With the 3X4 report I’ve better understood how my body was impacted with endurance training and fuelling types (protein vs. carbs) and diet inflammation issues such as gluten.”

Profile Picture

Arina

Verified

@arina

“I’ve never been petite. I’d go on a diet, lose weight, but I couldn’t maintain it. I always thought my willpower (or lack of it) was to blame. Only now, after my 3X4 experience, do I know there were lots of underlying reasons for my body’s resistance to weight loss. Since addressing them, I’ve lost 20 kilograms.”

Invest in Your Health With Confidence!

Eliminate guesswork and base your wellness approach on proven DNA evidence - get actionable guidelines now.

*Your purchase is eligible for HSA/FSA reimbursement, and your test ships totally free.

Swab DNA Test

Customer Frequently Asked Questions

Genetics make up the baseline “code” by which your body functions. The impact of every single choice you make throughout your life is influenced by your personal genetic makeup. We test over 157 genes that can affect your metabolism, inflammation, detoxification, fitness, weight, hormones, cognition, and response to your diet, and supplements. By understanding how your unique genetics impact these key processes, you can make smarter, more personalized decisions about your health. There may even be insights you never imagined (like whether that second cup of coffee is a good idea).

Our genetic test is designed to provide clear insights and recommendations about areas of health that are most important to you:

  • Nutrient needs
    What are your body’s unique needs and how do you respond to certain foods? How well do you tolerate fat and carbs? What’s your vitamin D need? Do you require extra antioxidants and Omega-3 fats compared to others? Should you limit gluten, salt, or caffeine?

  • Fitness strengths
    What type of exercise will your body respond best to? How can you train smarter in alignment with your genes, for better performance, faster recovery, and fewer injuries?

  • Proactive prevention
    Is your body more prone to high blood pressure, high blood sugar, or high cholesterol? How can you support your cardiovascular system and your immune system for more resilience as you age? We also look at processes like your inflammation, detoxification, methylation, and more.

  • Ideal Weight
    Why does your body resist weight loss and how can you manage your weight in a healthy way that is personalized to your unique body?

  • Stress strategies
    How does your life stress affect your brain health, your hormones, your sleep quality, and your overall wellness? More importantly, what can you do about it?

Click to download a 3X4 Sample Report

You do not need to see a 3X4 Practitioner to receive your report, but when your genetics insights are combined with your medical history, unique lifestyle, diet preferences, and exercise choices, a full picture starts to emerge. If you are looking for a detailed action plan, our practitioner partners are ready to guide you on your health journey.

Yes, it is eligible for HSA / FSA.

How can I use my HSA/FSA debit card?
You would use it in the same way you would use a credit card when paying, simply enter the needed card info. If this does not work, simply pay for the test with your normal credit card, download the invoice/receipt and submit that for reimbursement.


Will I be able to claim retrospectively as well?
HSA: As long as the HSA was established before you bought the 3X4 test, HSA can be used to reimburse that expense years later.

FSA: You can claim retrospectively as long as it falls within the current fiscal year.

I bought my test via my practitioner – can I still claim?
Most definitely. Simply ask for an itemized invoice from your practitioner where you can see the 3X4 test listed and the amount. Submit that claim for reimbursement.

Every gene has been selected based on 2 factors: scientific validity and actionability. The genes in the 3X4 Test were selected from peer-reviewed scientific publications. To ascertain scientific validity, we ensure that there is adequate research to understand what the gene does and how the version of the gene you possess affects your body. Every gene in your report has been hand-picked because there is a documented action you can take to reduce your risk and improve your health.

After sending in your genetic sample, results take 3-4 weeks to process.

Our partner lab securely retains your sample until we are sure we have complete and accurate results to produce a report.

The sample is automatically destroyed 6 months after we have received your results.

Please contact usand we will check our database to see whether your health practitioner has been previously certified to offer the 3X4 test. If not, we can introduce you to a practitioner in the 3X4 Network.

Our test kit is a simple and pain-free cheek swab that you can complete at home. A thorough rub with a sterile swab on the inside of each cheek for 60 seconds is all it takes. No spitting or blood draw is required.

Data privacy is a top priority for us. We treat your personal information with the rigor and integrity it deserves, and our practices, procedures, policies, and technology are designed to safeguard your privacy and health data. 

All information and connections are encrypted using SSL and we follow best practices that align with HIPAA and POPI standards. For more details, check out How 3X4 Protects Genetic Data and read through our Privacy Policy.

3X4 Genetics takes safeguarding all genetic data seriously. Read more about our policies and practices to protect client information here: How 3X4 Protects Genetic Data and in our Privacy Policy.

While genetic discrimination is rare, it is both common and understandable to want to know what protections are in place around the use of this type of information. In the United States, the Genetic Information Nondiscrimination Act, or GINA, protects all Americans from discrimination on the basis of genetic information when determining eligibility for employment and health insurance. It does not currently extend to life insurance, long-term care insurance, or disability insurance. State-level legislation varies and may provide additional protections.

For more information on GINA, we’ve created this resource: Genetic Information and Discrimination Protections

Please do not hesitate to get in touch! Please use our contact form or give us a call at (425) 818-5333.

You can choose to pay using Klarna. Klarna will provide you with specific payment terms. For further information or questions regarding your payment please visit Klarna’s website or contact Klarna’s customer service.